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Keybot 2 Résultats  ar2006.emcdda.europa.eu
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  Capà­tulo 8: Mejora del...  
Mientras que la heroína se une a los receptores de opiáceos del cerebro, como los receptores μ, y por lo tanto imita la acción de las endorfinas del cerebro, la cocaína, una vez ha producido su efecto, impide la reabsorción de la dopamina (y también de la serotonina) de la sinapsis neuronal.
In contrast to heroin addiction, which can be treated with agonists such as methadone or antagonists such as naltrexone, there are currently no medical treatments available for cocaine addiction. The reason for this would appear to be the mechanism of action through which cocaine exerts its effects on the brain neurotransmitters dopamine and serotonin. Whereas heroin binds to brain opioid receptors, such as the mu receptors, and therefore mimics the action of the brain’s own endorphins, cocaine inhibits the reabsorption of dopamine (and indeed serotonin) from the neuronal synapse once it has had its effect, leading to a build-up of the transmitter, thus prolonging and strengthening its effect.

Si la información recabada por el indicador de CPD se une a este conjunto más amplio de datos, el OEDT podrá avanzar en sus esfuerzos por mejorar el conocimiento general de la dimensión y la naturaleza de los problemas relacionados con la droga en Europa.
Given that many of the data sources available are based on behavioural reports of drug consumption, the concept of frequent or intensive use needs to be developed on this basis. This will widen the perspective for monitoring drug problems beyond that currently found in the PDU indicator. Locating the PDU information alongside this broader information set will also represent a step forward in the EMCDDA’s efforts to improve its overall understanding of both the scale and the nature of drug problems in Europe. In parallel, work needs to advance on developing reporting standards that enable patterns of polydrug use to be better described at the European level. The first steps in this direction include developing a more sophisticated conceptual framework for looking at different types of multiple drug consumption – including the adoption of appropriate temporal frameworks – and identifying appropriate data sources.