doses – -Translation – Keybot Dictionary

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  Bisphénol A – la mère t...  
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D’autant qu’une dose même modeste suffit à produire des effets sensibles. «Nous avons exposé des souris portantes à des doses comparables à celle que nous rencontrons dans notre environnement», explique la chercheuse.
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BPA is present in plastics, CDs, cooking utensils, etc—making it difficult for the mother to avoid contact with the chemical, and a relatively small dose produces significant effects. “We exposed lab mice to doses that are similar to those people have on a daily basis,” explains the researcher.
  Comprendre la propagati...  
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«Nous avons soumis les neurones à de grandes doses d’acide okadaïque, ce qui a provoqué leur mort dans les 24 à 48 heures. Il est toutefois tout à fait imaginable de réduire cette dose, et d’observer le résultat sur un laps de temps plus long», indique Anja Kunze, co-auteure de la publication.
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To “infect” one of the two interconnected cell cultures, one of the compartments was exposed to Okadaic Acid (OA). OA makes neurons exhibit one main characteristics of AD by causing hyperphosphorylation of the Tau proteins in the cells. This is a hallmark of AD, and it leads to the progressive destruction of the neural networks as well as the neurons themselves. “We exposed the neurons to high doses of OA, and it killed them within 24 to 48 hours,” says Anja Kunze, co-author of the article detailing the new method. “But we could also try lower exposure levels and observe the results over longer periods of time. Our results thus far show that the healthy cells were contaminated after 24 hours. But more observations are needed before drawing any conclusions.”
  Doser le poison au plus...  
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Les cancérologues font face au même problème, mais leurs buts sont opposés. En effet, de trop faibles doses de chimiothérapie, plutôt que de tuer les cellules malignes, induisent de dangereux mécanismes de résistance.
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King Mithridates understood that poison is only as good as the dosage taken. Each day, he ingested small quantities of poison in order to become immunize and escape his court’s plotters. Oncologists run up against the same principle when fighting cancer. Sometimes, a small dose of chemotherapy may induce dangerous resistance mechanisms in malignant cells, resulting in relapse. Now, EPFL research published in the journal PLOS ONE reports a tool that could simply and accurately determine the right dose for individual patients.
  Doser le poison au plus...  
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Les cancérologues font face au même problème, mais leurs buts sont opposés. En effet, de trop faibles doses de chimiothérapie, plutôt que de tuer les cellules malignes, induisent de dangereux mécanismes de résistance.
Compare text pagesCompare HTM pagesOpen source URLOpen target URLDefine actu.epfl.ch as primary domain
King Mithridates understood that poison is only as good as the dosage taken. Each day, he ingested small quantities of poison in order to become immunize and escape his court’s plotters. Oncologists run up against the same principle when fighting cancer. Sometimes, a small dose of chemotherapy may induce dangerous resistance mechanisms in malignant cells, resulting in relapse. Now, EPFL research published in the journal PLOS ONE reports a tool that could simply and accurately determine the right dose for individual patients.
  Le lait recèle une incr...  
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En outre, «malgré tous nos efforts, nous ne sommes pas parvenus à déceler d’effets secondaires» poursuit Carles Cantó. Même avec des doses dix fois supérieures à la quantité «efficace» du produit, aucun trouble ne s’est développé.
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These beneficial effects aren’t the only advantages of this “hidden vitamin.” The fact that it is naturally present in many foods will make it significantly easier for the public to accept its use in a nutritional or therapeutic context. In addition, “despite all our efforts, we were not able to detect side effects,” says Cantó. Even in quantities ten times over the “effective” dose, no adverse reactions were observed. “It really appears that cells use what they need when they need it, and the rest is set aside without being transformed into any kind of deleterious form,” explains the scientist. On that count, if used to improve cholesterol profiles, NR would have a decisive advantage over its “cousin” NA (nicotinic acid, or niacin), which is as effective, but has various side effects such as flushing.