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In 1983 Dr. Karel Ubik became the head of the MS Group. Organic mass spectrometry quickly developed. New ionization techniques as well as tandem MS/MS techniques were introduced. To keep pace with quick MS development, ZAB-EQ (VG analytical) sector mass spectrometer was purchased in 1987. Increasing importance of mass spectrometry made the MS group to grow rapidly. Dr. Karel Ubik and his group studied many organic compounds. Numerous natural compounds were identified by mass spectrometry, including volatile compounds, hydrocarbons and terpenes, flavonoids, saponins, steroids, alkaloids, peptides and others. Drugs synthesized in IOCB, including those with incredible biological functions, were studied in his laboratory. The instrument has been in service for 22 years. Analysis of biomolecules soon got into focus. MALDI-TOF spectrometer Reflex IV together with an automatic gel spot picker and digest station Proteineer (all Bruker) was purchased in 2002. The instruments were used for peptide mass fingerprinting as well as for analyzing other compounds.
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