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Posterior fossa syndrome (PFS) is also known as cerebellar mutism. PFS is the name given to a number of specific neurological problems that could occur after surgery. The main problem is the child's inability to speak (mutism). Other problems could include rapidly changing emotions (emotional lability), diminished muscle tone (hypotonia) and lack of muscle coordination (ataxia). It is not known why PFS develops, but it occurs to some degree in up to 25% of surgeries to remove posterior fossa tumours (medulloblastomas, ependymomas, and astrocytomas).
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