heme – -Translation – Keybot Dictionary

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Show textShow cached sourceOpen source URL	At the Science and Technology Session of the 2010 International Journal of Arts and Sciences (IJAS) Mediterranean Conference for Academic Disciplines, I presented the results of my research suggesting that the protein heme oxygenase-2 might be among the molecular targets of Pb in developing neuronal cells.
Compare text pagesCompare HTM pagesOpen source URLOpen target URLDefine hse.gcoe.kyoto-u.ac.jp as primary domain	鉛は、乳幼児に学習障害を発生させる原因となる物質であり、また神経毒性をもつことで有名な重金属のひとつです。そこで、私の研究の目的は、リスクアセスメントに用いることの可能な鉛の発育神経毒性に関するバイオマーカーを探索することです。2010年のInternational Journal of Arts and Science (IJAS)の地中海で行われた学会の科学分野（Science and Technology Session）で発表した論文中では、発達中の神経細胞に鉛を暴露した結果、ヘムオキシゲナーゼ-2がバイオマーカーとして有用である可能性を示しました。このIJASの学会では、私の論文について多くの人と議論する機会を得ることができただけでなく、多くの国の研究者と会うことができ、また、彼らの研究について学ぶこともでき、とても有意義な時間となりました。

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Show textShow cached sourceOpen source URL	Crystal structure of heme binding protein
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Recent investigations at different QM/MM levels address biocatalysis by heme enzymes (e.g., cytochrome P450), molybdopterin enzymes (e.g., xanthine oxidase), cystein proteases, fluorinases, lipases, chorismate mutase, p-hydroxybenzoate hydroxylase, and cyclohexanone monooxygenase.

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Auch wenn die QM/MM Technologie auf eine Vielzahl komplexer Systeme angewendet werden kann, interessieren wir uns hauptsächlich für enzymatische Reaktionen. In den letzten Jahren haben wir uns befasst mit der Biokatalyse durch Häm-Enzyme (z.B. Cytochrom P450), Molybdopterin-Enzyme (z.B. Xanthin-Oxidase), Cysteinproteasen, Fluorinasen, Lipasen, Chorismat-Mutase, p-Hydroxybenzoat-Hydroxylase und Cyclohexanon-Monooxygenase. Daneben untersuchen wir die spektroskopischen Eigenschaften von Proteinen mit QM/MM Methoden, beispielsweise die Raman-Spektren von Phycocyanin, die NMR-Spektren von Vanadium-haltigen Haloperoxidasen und die Elektronenspektren von fluoreszierenden Proteinen. Surface hopping QM/MM Simulationen erlauben darüber hinaus das Studium der Dynamik von elektronisch angeregten Chromophoren unter Einbeziehung der Umgebung.

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Show textShow cached sourceOpen source URL	Figure 5: Red blood cells contain hemoglobin molecules, a type of protein that transports oxygen from the lungs (via the heme) and carbon dioxide back to the lungs. image © ttsz/iStockphoto
Compare text pagesCompare HTM pagesOpen source URLOpen target URLDefine visionlearning.com as primary domain	Figura 5: Células rojas contienen moléculas de hemoglobina, un tipo de proteína que transporta oxigeno de pulmones (via el hemo) y el dióxido de carbono de regreso a pulmones. image © ttsz/iStockphoto

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Show textShow cached sourceOpen source URL	Figure 5: Red blood cells contain hemoglobin molecules, a type of protein that transports oxygen from the lungs (via the heme) and carbon dioxide back to the lungs. image © ttsz/iStockphoto
Compare text pagesCompare HTM pagesOpen source URLOpen target URLDefine visionlearning.com as primary domain	Figura 5: Células rojas contienen moléculas de hemoglobina, un tipo de proteína que transporta oxigeno de pulmones (via el hemo) y el dióxido de carbono de regreso a pulmones. image © ttsz/iStockphoto

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Show textShow cached sourceOpen source URL	The liver is the main and most important organ for the metabolism and the detoxification of the body. The metabolism of carbohydrates, lipids and amino acids, the detoxification of ammonia, and the degradation of cholesterol and heme are found in the liver.
Compare text pagesCompare HTM pagesOpen source URLOpen target URLDefine alavis.cz as primary domain	ALAVIS™ SAMMY ist ein veterinäres Mittel für Hunde und Katzen, das die Kombination der Stoffe SAM-e und Silybin – Extrakt aus Mariendistel – enthält. Beide Stoffe sind für ihren positiven Einfluss auf Leber und ihre Regeneration bekannt. Die Leber ist ein wesentliches und wichtigstes Organ für den Stoffwechsel und für die Detoxikation des Organismus. In Lebern finden der Stoffwechsel von Sachariden, Lipiden, Aminosäuren, die Detoxikation vom Ammoniak, die Degradation von Cholesterin, Häm statt, und weiterhin bilden sich in Lebern, degradieren und inaktivieren Hormone, es entstehen hier plasmatische Proteine und eine nicht weniger wichtige Funktion ist der Vorrat an Energie (Lipiden und Glykogen), Eisen und Vitaminen.
Compare text pagesCompare HTM pagesOpen source URLOpen target URLDefine alavis.cz as primary domain	ALAVIS™ SAMMY è un prodotto veterinario per cani e gatti contenente una combinazione delle sostanze SAM-e e Silibina - estratto di cardo mariano. Entrambe le sostanze sono note per il loro effetto positivo sul fegato e la sua rigenerazione. Il fegato è l'organo principale e più importante per il metabolismo e la disintossicazione del corpo. Nel fegato ha luogo il metabolismo dei carboidrati, lipidi, amminoacidi, ammoniaca, la disintossicazione dell‘ammoniaca, la degradazione del colesterolo, dell‘eme, inoltre nel fegato si creano, degradano e inattivano gli ormoni, qui si creano le proteine del plasma e una funzione non meno importante è l’immagazzinamento di energia (dei lipidi e del glicogeno), del ferro e delle vitamine.

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Show textShow cached sourceOpen source URL	Structure, dynamics and function of heme-proteins
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Show textShow cached sourceOpen source URL	Dr. Hyman Schipper has identified a potential trigger – elevated levels of an enzyme known as heme oxygenaze 1 (HO1) that appear early in the on-set of cognitive impairment.
Compare text pagesCompare HTM pagesOpen source URLOpen target URLDefine jghfoundation.org as primary domain	Le Dr Hyman Schipper a identifié un élément déclencheur potentiel – des taux élevés d’une enzyme appelée « hème oxygénase 1 (HO-1) », qui se manifeste dès l’apparition d’un trouble cognitif.

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Show textShow cached sourceOpen source URL	Where can you find heme iron?
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Show textShow cached sourceOpen source URL	"In Vitro Expression of some Heme Related Genes in Staphylococcus aureus mutants.", 110th General Meeting of American Society for Microbiology (ASM2010), Town & Country Convention Center, San Diego, CA, USA, May 23-27, 2010.
Compare text pagesCompare HTM pagesOpen source URLOpen target URLDefine www5.agr.gc.ca as primary domain	Diarra, M.S., Kobylarz, M., Allard, M., Rempel, H., Brouillette, É., Lacasse, P., et Malouin, F. (2010). « In Vitro Expression of some Heme Related Genes in Staphylococcus aureus mutants. », 110th General Meeting of American Society for Microbiology (ASM2010), Town & Country Convention Center, San Diego, CA, USA, May 23-27, 2010. (Affiche)

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Show textShow cached sourceOpen source URL	Where can you find heme iron?
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A new disease profile is added to our database – porphyria. Porphyria are inherited disorders, each involving a specific enzyme in the heme biosynthetic pathway. These disorders are classified as either hepatic or erythropoietic depending on the primary site of overproduction and accumulation of the porphyrin precursor or porphyrin, although some have overlapping features.

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Към нашата база данни е добавено ново рядко заболяване – Порфиринопатии. Порфиринопатиите представляват наследствени заболявания дължащи се на специфичен дефект на ензимите участващи в биосинтезата на хемоглобина. Те се класифицират в две основни групи: чернодробни и еритропоетични, в зависимост от мястото на първична свръхпродукция и натрупване на порфиринови прекурсори или порфирини. По-голяма част от хетерозиготните индивиди са без клинични симптоми, освен ако не бъдат изложени на фактори които могат да доведат до повишаване на производството на порфирини. Ендогенните и екзогенни полови стероиди, порфириногенни лекарства, прием на алкохол, ниско калорична диета, съпътстваща инфекция или оперативна интервенция обикновено могат да провокират клиничната изява на заболяването. За да получите пълното описание на болестта напълно безплатно натиснете тук и попълнете съответния модул. Oписанието е подготвено от нашия консултант по вътрешни болести – д-р Николай Ботушанов.

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Show textShow cached sourceOpen source URL	An anammox culture in a membrane bioreactor. The red color is due to the heme c group of the protein cytochrome c, that plays an important role in the anammox metabolism (Image courtesy of B. Kartal).
Compare text pagesCompare HTM pagesOpen source URLOpen target URLDefine mpi-bremen.de as primary domain	Anammox-Kultur in einem Membran-Bioreaktor. Für die rote Färbung ist die Häm c-Gruppe verantwortlich, die in dem Protein Cytochrom c, das im Anammox-Stoffwechsel eine wichtige Rolle spielt, enthalten ist (Foto B. Kartal).

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Show textShow cached sourceOpen source URL	to analyze the influence of heme and heme degradation products on acute renal failure in Stx-induced HUS (www.hhdp.uni-jena.de/index.php/acute-kidney-injury )
Compare text pagesCompare HTM pagesOpen source URLOpen target URLDefine septomics.de as primary domain	Den Einfluss von Häm und Hämabbauprodukten auf das akute Nierenversagen beim Stx-induzierten HUS zu analysieren (http://www.hhdp.uni-jena.de/index.php/acute-kidney-injury)

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Show textShow cached sourceOpen source URL	Spectral probes of heme protein dynamics.
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Show textShow cached sourceOpen source URL	Biophysical characterisation of multi-domain heme proteins.
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Show textShow cached sourceOpen source URL	Heme metabolism in stress regulation and protein production: from Cinderella to a key player
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Show textShow cached sourceOpen source URL	DHC Heme Iron, 60 Days' Worth
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  med.news.am  

Show textShow cached sourceOpen source URL	FoundationOne, a test for solid tumors, and FoundationOne Heme, a test for blood malignancies and pediatric cancers, help oncologists decide on a suitable chemotherapy treatment regimen based on a patient's genetic profile and predicted response.
Compare text pagesCompare HTM pagesOpen source URLOpen target URLDefine med.news.am as primary domain	Google решил не отставать от своих конкурентов: он предлагает своим сотрудникам и членам их семей, которым поставили онкологический диагноз, бесплатное исследование ДНК двух видов, стоимость которых составляет 5800-7200$. Первое исследование для тех, у кого обнаружили твердые опухоли, а второе касается злокачественных заболеваний крови у детей. Эти исследования дают онкологу наилучшую картину для определении природы опухоли, ее генетической природы и ожидаемой реакции организма на нее, а это обеспечивает наилучший подход к лечению болезни. Компания Google собирается возмещать эти расходы с января следующего года, сообщает Medical Daily.
Compare text pagesCompare HTM pagesOpen source URLOpen target URLDefine med.news.am as primary domain	Google-ը եւս որոշել է հետ չմնալ վերը նկարագրված մրցավազքից եւ իր՝ քաղցկեղով ախտորոշված աշխատակիցների եւ նրանց ընտանիքի անդամների համար ԴՆԹ-ի երկու տեսակի անվճար՝ 5800-7200 ԱՄՆ դոլար արժողություն ունեցող հետազոտություն առաջարկել: Դրանցից առաջինը կարծր ուռուցքների համար է, երկրորդը՝ արյան չարորակ նորագոյացությունների եւ մանկական քաղցկեղի: Հետազոտությունները օնկոլոգին լավագույն պատկերացումն են տալիս՝ հիվանդի գենետիկ պրոֆիլի եւ ակնկալվող ռեակցիայի վերաբերյալ եւ, ըստ այդմ, ամենաարդյունավետ բուժումն ընտրելու հնարավորությունն ընձեռում: Ընկերությունը մտադիր է նշված ծախսերը գալիք տարվա հունվար ամսից փոխհատուցել, հաղորդում է Medical Daily-ն:

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Iron comes in two forms, heme and non-heme. Non-heme iron is found in plants and is not as well absorbed as the heme iron found in animal products. Vitamin C helps switch iron to the ferrous state, which is more easily absorbed.

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Hay hierro en dos formas, hemo y no hemo. El hierro no hemo se encuentra en vegetales y no se absorbe tan bien como el hierro hemo, que se encuentra en productos animales. La vitamina C ayuda a convertir el hierro a su estado ferroso, que se absorbe más fácilmente. Quizás esta sea una de las combinaciones alimenticias más importante, dado que la falta de hierro es la deficiencia número uno entre los atletas de resistencia, especialmente entre las mujeres.

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Show textShow cached sourceOpen source URL	Charlotte Buron — Development of novel oxidation bioinspired catalysts : non heme iron(II) complexes grafted on golf electrode or β-lactoglobuline (2015)
Compare text pagesCompare HTM pagesOpen source URLOpen target URLDefine icmmo.u-psud.fr as primary domain	Charlotte Buron — Développement de nouveaux catalyseurs d'oxydation bioinspirés: Greffage de complexes de fer(II) non hémiques sur électrodes d'or ou dans la β-lactoglobuline (2015)

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Show textShow cached sourceOpen source URL	Immobilisation of heme proteins
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Show textShow cached sourceOpen source URL	Porphyrins are important biological building blocks for nature. Chlorophyll, the green photosynthetic pigment, and Heme, the red blood pigment, are just two examples of this class of chemical compounds.
Compare text pagesCompare HTM pagesOpen source URLOpen target URLDefine munich-photonics.de as primary domain	Porphyrine sind biologisch wichtige Bausteine -- unter anderem gehören Chlorophylle (Blattgrün) und Häme (roter Blutfarbstoff) zu dieser Klasse von chemischen Verbindungen.

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Show textShow cached sourceOpen source URL	Porphyrins are important biological building blocks for nature. Chlorophyll, the green photosynthetic pigment, and Heme, the red blood pigment, are just two examples of this class of chemical compounds.
Compare text pagesCompare HTM pagesOpen source URLOpen target URLDefine map.uni-muenchen.de as primary domain	Porphyrine sind biologisch wichtige Bausteine -- unter anderem gehören Chlorophylle (Blattgrün) und Häme (roter Blutfarbstoff) zu dieser Klasse von chemischen Verbindungen.

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Show textShow cached sourceOpen source URL	Micronutrients that are currently provided mainly by meat or dairy, and that could possibly be of potential concern when intake of meat and/or dairy is lowered, are heme iron, selenium, vitamin B1, vitamin B12, and zinc (meat), and calcium, vitamin B2, vitamin B12, phosphorus, vitamin A and zinc (dairy).
Compare text pagesCompare HTM pagesOpen source URLOpen target URLDefine legumechef.com as primary domain	I micronutrienti che attualmente sono forniti principalmente da carne e latticini e che possono essere un problema potenziale nel momento in cui si riduca il consumo di carne e/o latticini, sono il ferro eme, il selenio, la vitamina B1, la vitamina B2 e lo zinco (carne); il calcio, la vitamina B2, la vitamina B12, il fosforo, la vitamina A e lo zinco (latticini).

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For cytochrome b6, for example, another membrane protein that has a key role in the photosynthetic electron transport, the Freiburg researchers were able to elucidate the function of the heme cofactor in the protein folding process.

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Proteine wie Glycophorin A oder die Rezeptor-Tyrosinkinasen schaffen es offenbar alleine, Haltung anzunehmen. Andere jedoch brauchen Hilfe. Im Falle des Membranproteins Cytochrom b6, das eine wichtige Rolle beim Elektronentransport der Photosynthese spielt, konnten die Forscher um Schneider die Funktion des Kofaktors Häm bei der Proteinfaltung entschlüsseln. Häm ist eine Komplexverbindung, die in ihrem Zentrum ein Eisenatom besitzt und an verschiedene Proteine gebunden sein kann, wie etwa an Hämoglobin im Blut. Cytochrom b6 trägt zwei Häm-Gruppen. Außerdem besitzt es vier alpha-Helices, die in der Membran verankert sind. Durch eine Blockade der Bindungsstelle für den Cofaktor konnten Schneider und seine Mitarbeiter feststellen, dass Häm für die korrekte Faltung des Cytochroms in der Membran essenziell ist. Künstliche Aminosäureaustausche in verschiedenen Bereichen des Proteins enthüllten ihnen außerdem die einzelnen Schritte der Faltung und hierfür entscheidende Aminosäuren. In Zukunft möchten die Forscher herausfinden, ob und wie die vier alpha-Helices miteinander interagieren. „Ich möchte einmal jeden Schritt der Faltung eines Membranproteins nachvollziehen können“, sagt Schneider. „Vom Anfang bis zum Ende.“

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Chemically chlorophyll is a mixture of several highly complex molecules, which consist of a ring structure (the porphyrin structure) with a central magnesium ion, and a long hydrophobic side chain (Fig 2.). Chlorophyll is produced through the same metabolic pathway as other pigments such as heme, the red colour of blood (which has an iron ion in the ring structure).

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Chlorofil jest mieszaniną kilku złożonych cząsteczek o budowie pierścieniowej (układ porfiryny) z centralnie umiejscowionym jonem magnezowym i długim, bocznym łańcuchem hydrofobowym (Ryc.2). Chlorofil jest wytwarzany w podobnym cyklu metabolicznym jak inne barwniki, np. hem – czerwony barwnik krwi (w strukturę pierścieniową jest wbudowany jon żelaza). Chlorofil posiada kilka odmiennych form występujących w naturze, które nieznacznie różnią się między sobą strukturą pierścienia i bocznym łańcuchem (patrz Tabela 1).

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Show textShow cached sourceOpen source URL	Your child is growing, gaining weight, blood volume increases and its iron needs too. Consider giving him meat, source of heme iron, which is to say, the best form assimilated by the body.
Compare text pagesCompare HTM pagesOpen source URLOpen target URLDefine pediakid.com as primary domain	Votre enfant grandit, prend du poids, son volume sanguin augmente et ses besoins en fer aussi. Pensez à lui donner de la viande, source de fer héminique, c'est-à-dire la forme la mieux assimilée par l’organisme.

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Show textShow cached sourceOpen source URL	The Effect of Distal Interactions on O2-Binding to Heme
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Show textShow cached sourceOpen source URL	Authors: Layer,G. ; Reichelt,J. ; Jahn,D. ; Heinz,Dirk W. *; (Year: 2010). Title: Structure and function of enzymes in heme biosynthesis. Journal: Protein Science: Volume: 19 Issue: 6, S-Page: 1137-E-Page: 1161 PubMed
Compare text pagesCompare HTM pagesOpen source URLOpen target URLDefine helmholtz-hzi.de as primary domain	Autoren: Layer,G.; Reichelt,J.; Jahn,D.; Heinz,Dirk W.*; (Jahr: 2010). Titel: Structure and function of enzymes in heme biosynthesis. Zeitschrift: Protein Science: Band: 19 Heft: 6, S-Seite: 1137-E-Seite: 1161 PubMed