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Plusieurs études réalisées en milieu de travail ont indiqué que le toluène influait sur les paramètres neuro-comportementaux (tests de dextérité manuelle, de compétence visuelle et du champ d'attention) à des concentrations allant de 264 à 441 mg/m3 (Foo, Phoon et Lee, 1988; Foo, Jeyaratnam et Koh, 1990; Boey, Foo et Jeyaratnam, 1997; Eller, Netterstrom et Laursen, 1999; Kang et coll., 2005).
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Several occupational studies have reported effects of toluene on neurobehavioural endpoints (tests of manual dexterity, visual competency, and attention span) at concentrations ranging from 264 to 441 mg/m3 (Foo, Phoon and Lee 1988; Foo, Jeyaratnam and Koh 1990; Boey, Foo and Jeyaratnam 1997; Eller, Netterstrom and Laursen 1999; Kang et al. 2005). No effects were seen at concentrations ranging from 75 to 113 mg/m3 (Kang et al. 2005), nor was any difference seen between exposed workers (98 mg/m3) and a reference group (11 mg/m) (Seeber et al. 2004; Seeber et al. 2005).
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