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La neuropathie périphérique peut également être un effet secondaire de certains médicaments, particulièrement les antirétroviraux tels que le ddI, le d4T et le ddC, ainsi que d’autres médicaments utilisés dans le traitement des affections liées au VIH comme la thalidomide, Flagyl (métronidazole), la dapsone, l’isoniazide et les médicaments anticancéreux telle la vincristine.
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Peripheral neuropathy (PN) is a form of nerve damage usually felt as numbness, tingling, burning, or pain in the toes and feet, and sometimes in the fingers and hands. People with HIV can experience PN either because of the direct effects of HIV on the nervous system, at any stage of infection, or because of other infections and tumours that affect the nervous system. PN can also be a side effect of some drugs, especially the antiretrovirals ddI, d4T and ddC, as well other drugs used to treat HIV-related conditions, including thalidomide, Flagyl (metronidazole), dapsone, isoniazid, and anticancer drugs like vincristine. Recreational drugs such as alcohol, cocaine or amphetamines may contribute to PN.
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