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Cross-reactions have been rarely reported. Historically, the use of cataplasms was shown to induce allergy to mustard, documenting the reality of sensitization to food proteins by skin application. Single cases have been described of cross allergy to cauliflower, broccoli, coleslaw, cabbage, or to Brazil nuts, probably linked to similar allergens. A marked common reactivity has been shown between mustard and the major allergen of rapeseed. Colza-seeds have recently been introduced in appetizers; the use of colza-flour in vegetarian burgers is on the increase in the USA and is soon to be found in Europe : This should be kept in mind as they could change the situation. In two cases a mustard allergy occurred in patients sensitized to inhaled isocyanates, raising the hypothesis of a cross reaction with isothiocyanates of mustard seeds, but this still needs to be confirmed.
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