speer – Übersetzung – Keybot-Wörterbuch

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Das T6SS ist in der äusseren Membran von Bakterien fest verankert. Der winzige mit einer Spitze versehene Speer ist von einer flexiblen Hülle umgeben. «Wenn Bakterien ihre Harpune abfeuern, zieht sich die Hülle innert weniger Millisekunden zusammen und stösst so den Speer in Bakterien, die sich in unmittelbarer Nachbarschaft befinden», erklärt Basler den Mechanismus.
The T6SS is firmly attached to the bacterial cell envelop. The tiny spear with a sharp tip is surrounded by a flexible sheath. “When bacteria fire their spear guns, the sheath rapidly contracts in just a few milliseconds and ejects the spear out of the cell into by-standing bacteria,” says Basler describing the mechanism. “The attackers then recycle the harpoon proteins remaining in the cell.” In this maneuver, the bacteria also hit related bacterial strains that do the same as the attackers: They disassemble the harpoon into their protein components and reuse these for new T6SS assembly.
  Biozentrum: News Details  
Das T6SS ist in der äusseren Membran von Bakterien fest verankert. Der winzige mit einer Spitze versehene Speer ist von einer flexiblen Hülle umgeben. «Wenn Bakterien ihre Harpune abfeuern, zieht sich die Hülle innert weniger Millisekunden zusammen und stösst so den Speer in Bakterien, die sich in unmittelbarer Nachbarschaft befinden», erklärt Basler den Mechanismus.
The T6SS is firmly attached to the bacterial cell envelop. The tiny spear with a sharp tip is surrounded by a flexible sheath. “When bacteria fire their spear guns, the sheath rapidly contracts in just a few milliseconds and ejects the spear out of the cell into by-standing bacteria,” says Basler describing the mechanism. “The attackers then recycle the harpoon proteins remaining in the cell.” In this maneuver, the bacteria also hit related bacterial strains that do the same as the attackers: They disassemble the harpoon into their protein components and reuse these for new T6SS assembly.
  Biozentrum: News Details  
Dass eng verwandte Bakterien ihre Proteine durch diesen Harpunen-Beschuss austauschen und die Bestandteile wiederverwenden, konnten die Forscher nun erstmalig beim Erreger der Cholera, Vibrio cholerae, nachweisen. Dazu haben sie T6SS-defekte Bakterien, denen die Proteine für den Bau des Speers fehlten, mit normalen T6SS-produzierenden Vibrio-Bakterien zusammengebracht.
That closely related bacteria share their proteins through this type of spear gun attack and then recycle the components, has been demonstrated by the researchers for the first time, using the cholera pathogen, Vibrio cholerae. For this, they mixed T6SS-deficient bacteria that lack the proteins needed for the spear gun production with normal T6SS-producing Vibrio bacteria. “The special thing about Vibrio cholerae is that it assembles spear guns all the time and fires them aimlessly,” explains Andrea Vettiger, author of the study. “If one of T6SS-defecient bacteria is randomly hit, it disassembles the spear gun to its individual components, the shaft and tip proteins, and reassembles its own functional harpoon. Also the translocated tip-linked toxins can be recycled by the attacked cell. And even bacteria that no longer produce any proteins can assemble a T6SS by reusing the harpooned proteins provided by their neighboring sister cells.”