inactivé par – English Translation – Keybot Dictionary

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  4 Hits www.hc-sc.gc.ca  
Il peut aussi subir la dégradation microbienne et, en raison de la présence de l'ion paraquat chargé positivement, il est rapidement et complètement adsorbé sur les particules d'argile dans la couche supérieure du sol.4 Une fois inactivé par le sol, le paraquat ne disparaît que très lentement et il est peu probable qu'il atteigne la nappe phréatique par lixiviation.5
Paraquat applied to plant surfaces as the dichloride will undergo photochemical degradation to 4-carboxyl-1-methylpyridylium dichloride and methylamine hydrochloride.4 Paraquat may be microbially degraded before it is rapidly and completely adsorbed onto the clay particles in the top layer of the soil, because of the positively charged paraquat ion.4 Once inactivated by the soil, paraquat disappears only very slowly and is unlikely to leach to groundwater.5 Paraquat applied to aquatic systems disappears from the water rapidly, within six to 14 days, because of adsorption onto sediments and plants and uptake by plants.4
  4 Hits hc-sc.gc.ca  
Il peut aussi subir la dégradation microbienne et, en raison de la présence de l'ion paraquat chargé positivement, il est rapidement et complètement adsorbé sur les particules d'argile dans la couche supérieure du sol.4 Une fois inactivé par le sol, le paraquat ne disparaît que très lentement et il est peu probable qu'il atteigne la nappe phréatique par lixiviation.5
Paraquat applied to plant surfaces as the dichloride will undergo photochemical degradation to 4-carboxyl-1-methylpyridylium dichloride and methylamine hydrochloride.4 Paraquat may be microbially degraded before it is rapidly and completely adsorbed onto the clay particles in the top layer of the soil, because of the positively charged paraquat ion.4 Once inactivated by the soil, paraquat disappears only very slowly and is unlikely to leach to groundwater.5 Paraquat applied to aquatic systems disappears from the water rapidly, within six to 14 days, because of adsorption onto sediments and plants and uptake by plants.4
  www.cancer.ca  
La méthylation de l’ADN est une méthode employée pour réguler l’expression des gènes. La SPARC est un gène suppresseur de tumeur qui est inactivé par la méthylation. Les chercheurs ont étudié la SPARC en tant que moyen d’évaluation du pronostic.
Researchers have found that methylation markers, such as secreted protein acidic and rich in cysteine(SPARC), show promise in helping to find pancreatic cancer early. DNA methylation is commonly found in pancreatic cancer, as well as other types of cancer. DNA methylation is a method used to regulate gene expression. SPARC is a tumour suppressor gene that is inactivated through methylation. Researchers studied SPARC as a measure of prognosis. It also offers a potential future target for treating pancreatic cancer (Anticancer Research,PMID 20393008; Journal of Clinical Pathology, PMID 23135349; Cancer Letters, PMID 22939997; Journal of Clinical Oncology, PMID 21969517; Cancer Treatment Reviews, PMID 22226241).
  videoonline.edu.lmu.de  
En combinant des approches génomiques et protéomiques, nous avons identifié au moins 42 sous-unités dans complexe I de Chlamydomonas. Sauf pour ND2, toutes les sous-unités des mitochondriales (ND1, ND4, ND5 et ND6) ont été inactivé par mutagenèse aléatoire.
The researches of our lab are focusing on the characterization of respiratory components involved in the biogenesis of the complexes. Part of our efforts are devoted to the characterization of complex I. This complex is the less understood of all the enzymes of the respiratory chain, mainly because of its large size. By combining genomic and proteomic approaches, we have identified at least 42 subunits in Chlamydomonas complex I. Except for ND2, all the mitochondria-encoded subunits (ND1, ND4, ND5 and ND6) have been inactivated by random mutagenesis. We are now extending our work to nucleus-encoded subunits that present a particular interest, by using the RNA interference technique to silent the expression of the genes. We are also exploring the biogenesis of complex IV and are trying to elucidate the role of some chaperones involved in the delivery of copper to the enzyme.
  www.agr.ca  
De plus, un mutant du virus de la nécrose du concombre chez lequel le gène codant la p20 a été inactivé par knock-out a révélé une diminution de l’accumulation d’ARN viral chez les plantes infectées, ce qui concorde avec le rôle de la p20 dans la suppression du silençage de l’ARN.
The p20 protein encoded by the tombusvirus, Cucumber necrosis virus has previously been shown to be involved in host pathogenicity and shares sequence similarity with the Tomato bushy stunt virus p19 suppressor of silencing. Using a virus-induced gene silencing (VIGS) assay, we show that p20 is a viral suppressor of RNA silencing (VSR) in infected plants. In addition, a CNV p20-knockout mutant showed a decline in viral RNA accumulation in infected plants, consistent with the role of p20 in suppression of RNA silencing. However, unexpectedly, all GFP transgenic plants co-infiltrated with p20 and GFP displayed RNA silencing using an Agrobacterium-mediated silencing assay. Detailed RNA analysis of GFP mRNA levels in p20 agro-infiltrated plants revealed that p20 did initially display suppressor activity but this was rapidly overcome by RNA silencing. p20 expression levels in agro-infiltrated plants were shown to be approximately 50-fold lower than that of the TBSV p19 silencing suppressor, consistent with the notion that p20 dosage levels are not sufficient to suppress RNA silencing in the Agrobacterium-mediated system. Our results suggest that a viral-based VIGS assay may be required for identifying VSRs encoded by some plant viruses. Based on bioinformatics studies the mechanism of suppression of silencing by p20 is predicted to be similar to that of the TBSV p19 suppressor.