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Cette épreuve permet de détecter les types de VPH suivants : Risque élevé : 16, 18, 26, 30, 31, 33, 35, 39, 45, 51 52, 53, 56, 58, 59, 66, 67, 68, 69, 70, 73, 82, 85, 97 (Éléments de preuve suffisants ou limités démontrant une cancérogenèse chez l'humain : IARC, Bouvard et al Lancet Oncol. 2009; 10 :321-322) et d'autres types de faible ou risque inconnu: 6, 11, 13, 32, 40, 42, 43, 44, 54, 61, 62, 71, 72, 81, 83, 84, 86, 87, 89, 90, 91.
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Nested PCR followed by genotyping using Luminex technology (1) (www.luminexcorp.com). The precise HPV type(s) are reported. Presence of additional types other than the ones reported cannot be excluded. The detection limit is between 10 and 100 copies for most mucosal HPV types. This assay detects the following HPV types: High Risk: 16, 18, 26, 30, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 67, 68, 68, 69, 70, 73, 82, 85, 97 (Sufficient or limited evidence for human carcinogenesis according to IARC, Bouvard et al Lancet Oncol. 2009; 10:321-322) and other types of low or unknown risk: 6, 11, 13, 32, 40, 42, 43, 44, 54, 61, 62, 71, 72, 81, 83, 84, 86, 87, 89, 90, 91. Please note that when testing formalin-fixed specimens, the presence of HPV may not be detected due to the decreased sensitivity of the assay. Direct sequencing is also available on special request. Call in advance for information.
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