glucocorticoid – English Translation – Keybot Dictionary

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&nbsp;<a href='https://iate.europa.eu/home'>IATE</a> 2841
=> glucocorticoid

Keybot      40 Results   14 Domains
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Investigations of Glucocorticoid Action in GN
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28. November 2016 (STOP-FSGS)
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2013, (73). A chemical screening procedure for glucocorticoid signaling with a zebrafish larva luciferase reporter system
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4167-4178. Intramolecular Heck Couplings and Cycloisomerization Reactions of Bromodienes and Enynes with Tetrasubstituted Methylenecyclopropane Terminators: Efficient Syntheses of [3]Dendralenes.
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; Müller,Rolf*; (Jahr: 2012). Titel: Activity-guided screening of bioactive natural compounds implementing a new glucocorticoid-receptor-translocation assay and detection of new anti-inflammatory steroids from bacteria13943.
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Authors: Kaufmann,K.; Simmons,L.; Herrmann,J.; Schwar,G.; Luniak,N.; Müller,Rolf*; (Year: 2012). Title: Activity-guided screening of bioactive natural compounds implementing a new glucocorticoid-receptor-translocation assay and detection of new anti-inflammatory steroids from bacteria13943. Journal: Biotechnology Letters: Volume: 35 Issue: 1, S-Page: 11-E-Page: 20 DOI: 10.1007/s10529-012-1042-0 HZI repository PubMed
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Ein Beispiel für den enormen Vorteil lieferten die Forscher selbst, indem sie ihre Fischchen dem Umweltgift Tributyltin aussetzten. Diese Verbindung stört das Glucocorticoid-Signalsystem in einzelnen Zellen nicht.
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The importance of using an intact organism as test system should not be underestimated. When they exposed their fish to tributyltin, the researchers highlighted this important advantage. Tributyltin is a highly toxic biocide that does not affect the glucocorticoid signalling system in individual cells. However, the liver of an intact organism that is exposed to tributyltin converts the compound into dibutyltin, which negatively affects the processes happening around glucocorticoids and their receptors. This tributyltin effect would have gone undetected in cell cultures as it is only converted into its effective form in the liver. The chronic exposure of intact organisms to tributyltin can also have negative effects on the metabolic processes in the entire organism.