acr – -Translation – Keybot Dictionary

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  Bristol-Myers Squibb Ca...  
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adalimumab plus le MTX en fonction de l'ACR 20 à 12 mois. Les critères d'évaluation secondaires après un et deux ans comprenaient l'inhibition de la progression radiographique, l'innocuité, les réactions au site d'injection et la rétention.
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The primary endpoint of the study was to determine non-inferiority of abatacept plus MTX to adalimumab plus MTX based on ACR 20 at 12 months. Secondary endpoints at one and two years included inhibition of radiographic progression, safety, injection site reactions and retention.
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3 Orencia s'est révélé supérieur au placebo pour d'autres paramètres de mesure de l'activité de la PAR qui ne font pas partie des critères d'évaluation de la réponse ACR, comme la raideur matinale. L'activité de la maladie a aussi été évaluée par le score d'activité de la maladie (DAS28).
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3 Orencia was significantly better than placebo in other measures of rheumatoid arthritis disease activity not included in the ACR response criteria, such as morning stiffness. The level of disease activity was also assessed using the Disease Activity Score 28 (DAS28). In the AIM-study, a DAS28-defined remission (das28‹2.6) was achieved in 15% and 24% of Orencia treated patients compared with 3% and 2% of placebo patients at 6months and 12 months, respectively . In Attain Study, DAS28-defined remission was observed in 10% of Orencia treated patients compared with 1% of placebo patients at 6months.