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2,4,6-Trichlorophénol: On a classé le 2,4,6-trichlorophénol dans le Groupe II -- probablement cancérogène pour l'homme (données insuffisantes pour prouver son pouvoir cancérogène à l'égard de l'homme, mais suffisantes pour les animaux de laboratoire); on a prouvé que ce produit est cancérogène pour les rats mâles et pour les souris des deux sexes.13
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2,4,6-Trichlorophenol: 2,4,6-Trichlorophenol is classified in Group II -- probably carcinogenic to man (inadequate evidence in humans, sufficient evidence in animals); it has been shown to be carcinogenic to male rats and mice of both sexes.13 Incorporating a surface area correction and using the robust linear extrapolation model, one can calculate that the unit lifetime risk associated with the ingestion of 1 µg/L 2,4,6-TCP in drinking water ranges from 1.8 × 10-8 (based on hepatocellular carcinomas in female mice) to 4.3 × 10-7 (based on leukaemia in male rats)*.18 The estimated ranges of concentrations in drinking water corresponding to lifetime risks of 10-5, 10-6 and 10-7 for these same tumour types based on the model described above are as follows:
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