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Bütün vakalarda yenidoğanın akut fizyolojik skoru (YAFS) başlangıçta bir kez; Töllner sepsis skoru, tam kan sayımı, mutlak nötrofil sayısı (MNS), lenfosit, monosit ve eozinofil sayıları ve immatür/total nötrofil (I/T) oranı 0-5, 7, 10, 14.
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Material and Method: The prospective, double-blind, randomized and placebo controlled trial was performed on 31 neutropenic neonates with candidial sepsis administered G-CSF in 16 infants (group I) or placebo in 15 infants (group II). G-CSF therapy (5 µ g/kg/day, for 5 days) or placebo was administered as soon as the initial sepsis findings appeared. Liposomal-amphotericin B (L-AMB) treatment was started when candida determined in blood culture. Score for neonatal acute physiology (SNAP) was calculated at the beginning of the study. Töllner’s sepsis score, complete blood counts, absolute neutrophil count (ANC), lymphocyte, monocyte and eosinophil counts, immature to total neutrophil ratio (I/T) were performed or calculated on the 0 to to 5, 7, 10, 14, 21th days.
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