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This revised and expanded classification of brain tumors is therefore up-to-date and important, because, previously, tumors were classified purely on the basis of histological characteristics, without taking adequate account of new molecular changes. Hainfellner: “Using the methods of precision medical diagnostics, that is to say DNA sequencing and epigenetic analyses plus histology, it became increasingly clear that the known types of tumor can be divided into an expanding number of subtypes with different prognoses. The new methods allow us to determine the nature of the different diseases more precisely, along with their molecular causes. That allows more accurate application of the available therapies and better prognoses for the patients affected.”
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