mapt – -Translation – Keybot Dictionary

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  www.robinpepinieres.com  
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Methods borrowed from big data and data analytics with a view to inferring paradigmatic splits – MAPT project
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Méthodes empruntées au big data et au data analytics pour l’inférence de ruptures paradigmatiques – Projet MAPT
  2 Hits www.uni-muenster.de  
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Bröcker, M.,  Bulle, F., Gärtner, C.,  Keasling, A. (2009). What is the geological significance of Cretaceous U–Pb zircon ages in  HP mélanges from the Cycladic blueschist belt, Greece? MAPT meeting, Edinburgh.
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Smit, M.A., Scherer, E.E., Bröcker, M., van Roermund, H.L.M. (2009). Evidence for early Caledonian eclogite facies metamorphism in the southernmost Scandinavian Caledonides from Lu-Hf and Sm-Nd geochronology. MAPT meeting, Edinburgh.
  5 Hits wwwfr.uni.lu  
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The researchers encountered a gene that could be an important determinant for the gender-specific differences in Alzheimer’s disease pathology. The gene, called ubiquitin-specific peptidase 9 (USP9), influences the activity of another gene that encodes the microtubule associated protein tau (MAPT).
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Die Forscher stießen auf ein Gen, das als wichtiger Einflussfaktor für die geschlechtsspezifischen Unterschiede in Bezug auf Alzheimer infrage kommt. Das Gen namens Ubiquitin-spezifische Peptidase 9 (USP9) beeinflusst die Aktivität eines Gens, welches das Tau-Protein kodiert (Mikrotubuli-assoziertes Protein Tau, MAPT). MAPT wiederum ist vermutlich stark an Entstehung der Alzheimer-Krankheit beteiligt.
  3 Hits www.taalbegintthuis.nl  
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Mutations in 3 genes are responsible for most of the FTD genetic cases: microtubule associated protein tau (MAPT), progranulin (PGRN) and chromosome 9 open reading frame 72 (C9orf72). Genetic or sporadic FTDs share common neuropathological features such as neuronal Tubulin-Associated Unit (TAU), Tar-DNA binding Protein 43 (TDP43), or Fused in Sarcoma (FUS) inclusions.
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Up to 50% of ALS patients develop FTD symptoms and around 15% of FTD patients display motor neuron dysfunction typical of ALS. To date, no treatment is available for these disorders, and the molecular mechanisms at stake in the different pathological subtypes remain elusive.
  www.gelatomuseum.com  
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Frailty, as opposed to complete dependence, is an important area to focus on as the The Multidomain Alzheimer Preventive Trial (MAPT) by Bruno Vellas in France and the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Decline (FINGER) by Miia Kivipelto in Sweden attest.
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« Une manière de surmonter ce problème consisterait à proposer différents produits adaptés aux différentes étapes de la vie, ajoute-t-il. Le diagnostic médical serait ici primordial, mais ne suffirait pas, à lui seul, à déterminer si une personne perdra ou non son autonomie. Sans compter que de nombreux pays ont durci leurs critères d’éligibilité ces dernières années, refusant aujourd’hui à des patients une prise en charge au titre de leur dépendance ou le remboursement des frais médicaux auxquels ils pouvaient prétendre auparavant. » Ce qui produit une autre source d’hétérogénéité dans les études longitudinales.
  28 Hits www.uantwerpen.be  
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Up to 50% of FTD patients have a positive family history for dementia and in the majority of these families the disease is inherited in an autosomal dominant fashion. So far only mutations in the microtubule associated protein tau gene (MAPT) on chromosome 17q21 have been identified for FTD linked to chromosome 17, with a frequency of 10 tot 43% in familial FTD.
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Frontotemporale dementie (FTD) is de tweede meest frequente vorm van neurodegeneratieve dementie in mensen jonger dan 65 jaar. Tot 50% van de FTD patiënten hebben een positieve familie historiek voor dementie en in de meerderheid van de families wordt de ziekte op autosomaal dominante wijze overgeërfd. Tot nu toe werd alleen mutaties in het microtubuli geassocieerde proteïne tau (MAPT) gen op chromosoom 17q21 geïdentificeerd als causaal voor FTD gekoppeld aan chromosoom 17, met een frequentie van 10 tot 43% in familiale FTD. In een aantal autosomaal dominante FTD families met 17q21 koppeling werden geen MAPT mutaties gedetecteerd (FTDU-17). Met het voorgestelde project willen we verder onderzoek doen naar het genetisch defect bij FTDU-17. We zullen de strategie volgen van positionele klonering in autosomaal dominante FTD families.
  2 Hits www.taschen.com  
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Werner Aisslinger, Atelier Bow Wow, Aybar Mateos, Cecil Balmond, Shigeru Ban, Bernardes Jacobsen, BIG, Alberto Campo Baeza, Carmody Groarke, Santiago Cirugeda, Coop Himmelblau, Diller Scofidio + Renfro, Ecosistema Urbano, Olafur Eliasson, Ammar Eloueini, Essentia, Established & Sons, Fantastic Norway, Mark Fisher, Massimiliano Fuksas, Laurent Grasso & Pascal Grasso, Zaha Hadid, Heatherwick, Institute of Computational Design, Toyo Ito, Adam Kalkin, Ken Min Architects, Koers Mulder, Adolf Krischanitz, Liu Jiakun, LOT-EK, MAPT, Miralles Tagliabue, MOS, Eric Owen Moss, NASA, Ivan Navarro, Jean Nouvel, OBRA Architects, OMA, OMD, John Pawson, Philippe Rahm, Raumlabor Berlin, Francesc Rifé, Michael Rojkind, Rotor, Tomas Saraceno, SO-IL, Tamassociati, Javier Terrados Cepeda, UNStudio, Helena Willemeit, Tokujin Yoshioka
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Werner Aisslinger, Atelier Bow Wow, Aybar Mateos, Cecil Balmond, Shigeru Ban, Bernardes Jacobsen, BIG, Alberto Campo Baeza, Carmody Groarke, Santiago Cirugeda, Coop Himmelblau, Diller Scofidio + Renfro, Ecosistema Urbano, Olafur Eliasson, Ammar Eloueini, Essentia, Established & Sons, Fantastic Norway, Mark Fisher, Massimiliano Fuksas, Laurent Grasso & Pascal Grasso, Zaha Hadid, Heatherwick, Institute of Computational Design, Toyo Ito, Adam Kalkin, Ken Min Architects, Koers Mulder, Adolf Krischanitz, Liu Jiakun, LOT-EK, MAPT, Miralles Tagliabue, MOS, Eric Owen Moss, NASA, Ivan Navarro, Jean Nouvel, OBRA Architects, OMA, OMD, John Pawson, Philippe Rahm, Raumlabor Berlin, Francesc Rifé, Michael Rojkind, Rotor, Tomas Saraceno, SKM, SO-IL, Tamassociati, Javier Terrados Cepeda, UNStudio, Helena Willemeit, Tokujin Yoshioka
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Werner Aisslinger, Atelier Bow Wow, Aybar Mateos, Cecil Balmond, Shigeru Ban, Bernardes Jacobsen, BIG, Alberto Campo Baeza, Carmody Groarke, Santiago Cirugeda, Coop Himmelblau, Diller Scofidio + Renfro, Ecosistema Urbano, Olafur Eliasson, Ammar Eloueini, Essentia, Established & Sons, Fantastic Norway, Mark Fisher, Massimiliano Fuksas, Laurent Grasso & Pascal Grasso, Zaha Hadid, Heatherwick, Institute of Computational Design, Toyo Ito, Adam Kalkin, Ken Min Architects, Koers Mulder, Adolf Krischanitz, Liu Jiakun, LOT-EK, MAPT, Miralles Tagliabue, MOS, Eric Owen Moss, NASA, Ivan Navarro, Jean Nouvel, OBRA Architects, OMA, OMD, John Pawson, Philippe Rahm, Raumlabor Berlin, Francesc Rifé, Michael Rojkind, Rotor, Tomas Saraceno, SKM, SO-IL, Tamassociati, Javier Terrados Cepeda, UNStudio, Helena Willemeit, Tokujin Yoshioka
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Werner Aisslinger, Atelier Bow Wow, Aybar Mateos, Cecil Balmond, Shigeru Ban, Bernardes Jacobsen, BIG, Alberto Campo Baeza, Carmody Groarke, Santiago Cirugeda, Coop Himmelblau, Diller Scofidio + Renfro, Ecosistema Urbano, Olafur Eliasson, Ammar Eloueini, Essentia, Established & Sons, Fantastic Norway, Mark Fisher, Massimiliano Fuksas, Laurent Grasso & Pascal Grasso, Zaha Hadid, Heatherwick, Institute of Computational Design, Toyo Ito, Adam Kalkin, Ken Min Architects, Koers Mulder, Adolf Krischanitz, Liu Jiakun, LOT-EK, MAPT, Miralles Tagliabue, MOS, Eric Owen Moss, NASA, Ivan Navarro, Jean Nouvel, OBRA Architects, OMA, OMD, John Pawson, Philippe Rahm, Raumlabor Berlin, Francesc Rifé, Michael Rojkind, Rotor, Tomas Saraceno, SKM, SO-IL, Tamassociati, Javier Terrados Cepeda, UNStudio, Helena Willemeit, Tokujin Yoshioka